Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59952 | 0.82 | RAB9A (0.66) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL29489449 | 0.82 | RAB9A (0.66) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14355062 | 0.82 | CCNE1 (0.46) | CCNE1CDK2CDK5ALDH1A1MAPT | |
| SCHEMBL59145 | 0.82 | KMT2A (0.49) | CCNE1CDK2CDK5ALDH1A1MAPT | |
| SCHEMBL32671808 | 0.82 | KMT2A (0.49) | CCNE1CDK2CDK5ALDH1A1MAPT | |
| SCHEMBL29739273 | 0.82 | MEN1 (0.51) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL5788823 | 0.82 | RAB9A (0.58) | CCNE1CDK2CDK5ALDH1A1MAPT | |
| SCHEMBL16172589 | 0.82 | MAPT (0.57) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL20644592 | 0.82 | CCNE1 (0.46) | CCNE1CDK2CDK5ALDH1A1MAPT | |
| SCHEMBL29935156 | 0.79 | RAD51 (0.52) | CCNE1CDK2CDK5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158844-A1 | HETEROCYCLIC COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 2012-11-22 | — | — | WO | disclosed |