Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471288 | 0.89 | GPR119 (0.57) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL13853614 | 0.88 | GPR119 (0.56) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL21966981 | 0.88 | GPR119 (0.60) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL8470834 | 0.88 | GPR119 (0.55) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL27118563 | 0.87 | GPR119 (0.55) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL29037711 | 0.85 | NAMPT (0.69) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL29498206 | 0.84 | GPR119 (0.57) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL12913022 | 0.83 | GPR119 (0.60) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL12082170 | 0.83 | GPR119 (0.79) | GPR119NAMPTMEN1KMT2AMAPT | |
| SCHEMBL30208161 | 0.83 | GPR119 (0.79) | GPR119NAMPTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841752-B1 | 3,4-DIHYDRO-2-NAPHTHAMIDE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2008-12-10 | — | — | EP | disclosed |