Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397978 | 0.88 | HRH3 (0.83) | HRH3CYP2D6 | |
| SCHEMBL1375830 | 0.87 | HRH3 (0.82) | HRH3CYP2D6 | |
| SCHEMBL1379627 | 0.87 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL1379480 | 0.86 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL5024332 | 0.85 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL5023298 | 0.85 | HRH3 (0.82) | HRH3CYP2D6 | |
| SCHEMBL1397944 | 0.84 | HRH3 (0.80) | HRH3CYP2D6 | |
| SCHEMBL1376244 | 0.83 | HRH3 (0.77) | HRH3CYP2D6 | |
| SCHEMBL5017143 | 0.83 | HRH3 (0.80) | HRH3CYP2D6 | |
| SCHEMBL1397975 | 0.83 | HRH3 (0.79) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957479-B1 | 1,5-SUBSTITUTED INDOL-2-YL AMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | claimed |