SCHEMBL13980076

SCHEMBL13980076

Cc1cc(Nc2ccccc2)nc(Nc2ccc(S(=O)(=O)O)cc2)c1C#N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
SNCA P37840 1/20 0.46
KDM4E B2RXH2 6/20 0.46
HSD17B10 Q99714 5/20 0.46
HPGD P15428 4/20 0.46
GAA P10253 2/20 0.46
PDE4B Q07343 1/20 0.44
PDE4D Q08499 1/20 0.44
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA13 Q8N1Q1 2/20 0.42
TSHR P16473 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
CA7 P43166 1/20 0.40
CCNA2 P20248 1/20 0.40
CDK2 P24941 1/20 0.40
CCNA1 P78396 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1498006 0.95 ALDH1A1 (0.50) ALDH1A1SNCAKDM4EHSD17B10HPGD
SCHEMBL15626618 0.91 ALDH1A1 (0.56) ALDH1A1SNCAKDM4EHSD17B10HPGD
SCHEMBL15629708 0.87 ALDH1A1 (0.50) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL1497998 0.87 ALDH1A1 (0.76) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL13810336 0.82 ALDH1A1 (0.49) ALDH1A1SNCAKDM4EPDE4BPDE4D
SCHEMBL12111403 0.82 ALDH1A1 (0.49) ALDH1A1SNCAKDM4EPDE4BPDE4D
SCHEMBL15629539 0.81 TSHR (0.46) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL14527672 0.81 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10HPGDGAA
SCHEMBL15626633 0.80 ALDH1A1 (0.44) ALDH1A1SNCAKDM4EHSD17B10HPGD
SCHEMBL14389565 0.79 HSD17B10 (0.42) ALDH1A1SNCAKDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1681322-B1 Ink jet ink and ink jet recording method FUJIFILM CORP (JP) 2008-12-24 EP disclosed