Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17547721 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL13926098 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL16367585 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL12116872 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL17342342 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL24604607 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL13971248 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL12359819 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL13104087 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 | |
| SCHEMBL2754594 | 1.00 | G6PD (0.57) | G6PDGAACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601669-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS, FORMULATIONS AND USES THEREOF FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA | SCHERING CORP (US) | 2008-12-24 | — | — | EP | disclosed |
| EP-1859796-A2 | TREATMENT OF XANTHOMA WITH AZETIDINONE DERIVATIVES AS STEROL ABSORPTION INHIBITORS | SCHERING CORPORATION (US) | 2007-11-28 | — | — | EP | disclosed |
| EP-1810971-A1 | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia | SCHERING CORPORATION (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1785144-A2 | Combinations of bile acids sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications | Shering Corporation (US) | 2007-05-16 | — | — | EP | disclosed |