Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 18/20 | 0.72 |
| ▸ | ESR1 | P03372 | 17/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922669 | 0.87 | ESR1 (0.72) | ESR2ESR1CYP3A4 | |
| SCHEMBL3939004 | 0.84 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL13980442 | 0.84 | ESR1 (0.67) | ESR2ESR1 | |
| SCHEMBL3931988 | 0.80 | ESR1 (1.00) | ESR2ESR1CYP3A4 | |
| SCHEMBL3935342 | 0.76 | ESR1 (1.00) | ESR2ESR1 | |
| SCHEMBL3933585 | 0.72 | ESR2 (0.68) | ESR2ESR1 | |
| SCHEMBL3934214 | 0.70 | ESR2 (0.69) | ESR2ESR1 | |
| SCHEMBL13980468 | 0.70 | ESR1 (0.64) | ESR2ESR1 | |
| SCHEMBL3921715 | 0.69 | ESR1 (0.68) | ESR2ESR1 | |
| SCHEMBL3932733 | 0.69 | ESR1 (0.68) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458700-B1 | SUBSTITUTED 2-PHENYL BENZOFURANS AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-12-03 | — | — | EP | disclosed |