Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922669 | 0.84 | ESR1 (0.72) | ESR1ESR2 | |
| SCHEMBL13980441 | 0.84 | ESR2 (0.72) | ESR1ESR2 | |
| SCHEMBL3939004 | 0.81 | ESR2 (1.00) | ESR1ESR2 | |
| SCHEMBL3931988 | 0.79 | ESR1 (1.00) | ESR1ESR2CYP1B1 | |
| SCHEMBL3935342 | 0.73 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL3933585 | 0.69 | ESR2 (0.68) | ESR1ESR2 | |
| SCHEMBL3932733 | 0.69 | ESR1 (0.68) | ESR1ESR2 | |
| SCHEMBL3934214 | 0.67 | ESR2 (0.69) | ESR1ESR2CYP1B1 | |
| SCHEMBL13980468 | 0.67 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL3934297 | 0.67 | ESR1 (0.65) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458700-B1 | SUBSTITUTED 2-PHENYL BENZOFURANS AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-12-03 | — | — | EP | disclosed |