Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.66 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043558 | 1.00 | ADRB2 (0.66) | ADRB2ADRB1DRD3 | |
| SCHEMBL10215353 | 0.89 | ADRB2 (0.63) | ADRB2ADRB1DRD3 | |
| SCHEMBL14291930 | 0.84 | ADRB2 (0.75) | ADRB2ADRB1DRD3 | |
| SCHEMBL27830246 | 0.84 | ADRB2 (0.62) | ADRB2ADRB1DRD3 | |
| SCHEMBL27809795 | 0.84 | ADRB2 (0.62) | ADRB2ADRB1DRD3 | |
| SCHEMBL4718496 | 0.81 | ADRB2 (0.59) | ADRB2ADRB1DRD3 | |
| SCHEMBL1803582 | 0.81 | ADRB2 (0.71) | ADRB2ADRB1DRD3 | |
| SCHEMBL1803584 | 0.81 | ADRB2 (0.71) | ADRB2ADRB1DRD3 | |
| SCHEMBL3688288 | 0.81 | ADRB2 (0.62) | ADRB2ADRB1DRD3 | |
| Hydrochloric Acid SCHEMBL1796166 | 0.80 | ADRB2 (0.69) | ADRB2ADRB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149110-A1 | BICYCLOR [2.2.1] HEPT-7-YLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES AND CONDITIONS IN WHICH M3 MUSCARINIC RECEPTOR ACTIVITY AND BETA-ADRENERGIC ACTIVITY ARE IMPLICATED | ARGENTA DISCOVERY LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008096127-A2 | BICYCLO[2.2.1]HEPT-7-YLAMINE DERIVATIVES AND THEIR USE AS M3 MUSCARINIC RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008017824-A1 | BICYCLO [2. 2. 1] HEPT-7-YLAMINE DERIVATIVES AND THEIR USE | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008017827-A2 | AZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-14 | — | — | WO | disclosed |