Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982703 | 0.85 | SMN1; SMN2 (0.46) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13983162 | 0.85 | RAB9A (0.48) | MAPTSMN1; SMN2RAB9AKMT2ANPC1 | |
| SCHEMBL13982735 | 0.84 | SMN1; SMN2 (0.45) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13982730 | 0.84 | KMT2A (0.45) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13982697 | 0.83 | MAPT (0.49) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13983281 | 0.81 | MAPT (0.48) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13982760 | 0.80 | MAPT (0.46) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13982779 | 0.80 | MAPT (0.50) | MAPTHPGDSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13982737 | 0.79 | RAB9A (0.41) | MAPTSMN1; SMN2RAB9AKMT2ANPC1 | |
| SCHEMBL13983081 | 0.79 | KMT2A (0.43) | MAPTHPGDSMN1; SMN2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |