Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FABP2 | P12104 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635844 | 0.91 | PPARA (0.53) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13984041 | 0.85 | PPARA (0.45) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13983873 | 0.83 | PPARA (0.53) | ALDH1A1SMN1; SMN2MAPTUSP2PPARA | |
| SCHEMBL13984047 | 0.82 | PPARA (0.43) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13983837 | 0.78 | PPARA (0.52) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13983835 | 0.77 | PPARA (0.56) | ALDH1A1SMN1; SMN2MAPTUSP2PPARA | |
| SCHEMBL13983696 | 0.76 | PPARA (0.56) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL12634588 | 0.76 | PPARA (0.55) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13928059 | 0.74 | PPARA (0.51) | ALDH1A1POLBSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13983707 | 0.74 | PPARA (0.53) | ALDH1A1SMN1; SMN2MAPTUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157537-A2 | COMPOSITIONS AND METHODS OF USE FOR TREATING OR PREVENTING LIPID RELATED DISORDERS | IRONWOOD PHARMACEUTICALS, INC (US) | 2008-12-24 | — | — | WO | disclosed |