Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.52 |
| ▸ | FABP2 | P12104 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983696 | 0.83 | PPARA (0.56) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL11714726 | 0.83 | PPARA (0.61) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL4755781 | 0.82 | PPARA (0.66) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL10270139 | 0.81 | PPARA (0.78) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL11716530 | 0.80 | MAPT (0.59) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL21413784 | 0.80 | PPARA (0.62) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL15682195 | 0.79 | ALDH1A1 (0.52) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL13983712 | 0.78 | ALDH1A1 (0.45) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL13983694 | 0.78 | PPARA (0.59) | PPARAFABP2PPARGSLC22A12MAPT | |
| SCHEMBL11712579 | 0.78 | PPARA (0.55) | PPARAFABP2PPARGSLC22A12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157537-A2 | COMPOSITIONS AND METHODS OF USE FOR TREATING OR PREVENTING LIPID RELATED DISORDERS | IRONWOOD PHARMACEUTICALS, INC (US) | 2008-12-24 | — | — | WO | disclosed |