Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985101 | 0.89 | PRKD3 (0.53) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13984937 | 0.85 | PKM (0.47) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13985098 | 0.85 | GAA (0.51) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3644534 | 0.85 | MAPT (0.74) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12847465 | 0.84 | HDAC1 (0.45) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13984896 | 0.81 | CDK2 (0.43) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12790537 | 0.81 | KMT2A (0.51) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL700587 | 0.78 | CDK2 (0.69) | PRKD3CDK2FLT3GSK3AGSK3B | |
| SCHEMBL12789774 | 0.78 | MAPT (0.76) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL700138 | 0.77 | CDK2 (0.48) | MAPTKDM4EALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | disclosed |