Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.51 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12790549 | 0.92 | CDK2 (0.48) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL13985098 | 0.90 | GAA (0.51) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL12790556 | 0.86 | HDAC1 (0.56) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL13984942 | 0.86 | HDAC6 (0.44) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL13984894 | 0.84 | CDK2 (0.42) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL13985101 | 0.84 | PRKD3 (0.53) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL4201089 | 0.83 | PRKD3 (0.52) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL3688533 | 0.82 | CSNK2A1 (0.76) | CDK2PRKD3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL13984939 | 0.82 | PKM (0.48) | FLT3IRAK4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12790555 | 0.81 | HDAC1 (0.40) | CDK2PRKD3MAP4K4PIM1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | disclosed |