Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 13/20 | 0.84 |
| ▸ | DRD1 | P21728 | 7/20 | 0.84 |
| ▸ | DRD2 | P14416 | 5/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.79 |
| ▸ | DRD4 | P21917 | 2/20 | 0.79 |
| ▸ | DRD5 | P21918 | 2/20 | 0.79 |
| ▸ | DRD3 | P35462 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742506 | 0.92 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| SCHEMBL2742549 | 0.89 | F3 (0.82) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Tetrahydroberberine SCHEMBL30484836 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Canadine SCHEMBL29365824 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Tetrahydroberberine SCHEMBL30302597 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Tetrahydroberberine SCHEMBL232164 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Tetrahydroberberine SCHEMBL14184002 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Canadine SCHEMBL432394 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| Tetrahydroberberine SCHEMBL2786492 | 0.88 | F3 (1.00) | F3DRD1DRD2CYP1A2CYP3A4 | |
| SCHEMBL2742548 | 0.88 | F3 (0.82) | F3DRD1DRD2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002873-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING LIPID LEVELS | CVI PHARMACEUTICALS LIMITED (KY) | 2008-12-31 | — | — | WO | disclosed |