Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 14/20 | 0.79 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.79 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.79 |
| ▸ | PTGIR | P43119 | 5/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017287 | 0.81 | ADRA2A (0.79) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL11180468 | 0.81 | ADRA2A (0.85) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL11248135 | 0.81 | PTGIR (0.82) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL13293426 | 0.81 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL4779741 | 0.81 | ADRA2A (0.79) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL13024513 | 0.81 | ADRA2A (0.79) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL1036359 | 0.81 | ADRA2A (0.78) | ADRA2AADRA2BADRA2CPTGIRADRA1D | |
| SCHEMBL13017196 | 0.80 | ADRA2A (0.81) | ADRA2AADRA2BADRA2CPTGIR | |
| SCHEMBL13017291 | 0.80 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CPTGIR | |
| SCHEMBL13062807 | 0.79 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CPTGIRADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156676-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING O-GLYCOSYLATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-12-24 | — | — | WO | disclosed |