Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.33 |
| ▸ | HTR2B | P41595 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851425 | 0.73 | CDA (0.41) | HTR2CHTR2BTP53HTR2AACVRL1 | |
| SCHEMBL6966920 | 0.70 | TP53 (0.38) | HTR2CHTR2BTP53HTR2AFPR2 | |
| SCHEMBL13655678 | 0.70 | HTR2C (0.34) | HTR2CHTR2BTP53HTR2AACVRL1 | |
| SCHEMBL994623 | 0.67 | HTR2C (0.40) | HTR2CHTR2BTP53HTR2AACVRL1 | |
| SCHEMBL651023 | 0.67 | HTR2C (0.49) | HTR2CHTR2BHTR2A | |
| SCHEMBL30178303 | 0.67 | HTR2C (0.49) | HTR2CHTR2BHTR2A | |
| SCHEMBL20707948 | 0.66 | — | — | |
| SCHEMBL14498122 | 0.66 | DRD2 (0.42) | HTR2CHTR2B | |
| SCHEMBL21966127 | 0.66 | HTR2C (0.43) | HTR2CHTR2BTP53HTR2A | |
| SCHEMBL2258692 | 0.66 | HTR2C (0.53) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |