Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757749 | 0.83 | CALCRL (0.38) | SMN1; SMN2NOTUMMEN1KMT2AMAPT | |
| SCHEMBL13985253 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2NOTUMMEN1KMT2AGAA | |
| SCHEMBL13985036 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2NOTUMMEN1KMT2AGAA | |
| SCHEMBL24987981 | 0.78 | SMN1; SMN2 (0.76) | SMN1; SMN2MEN1KMT2AGAAMAPT | |
| SCHEMBL23500811 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2NOTUMMEN1KMT2AGAA | |
| SCHEMBL13985082 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AGAAMAPT | |
| SCHEMBL13985180 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAMAPTHSD17B10TSHR | |
| SCHEMBL28987840 | 0.75 | SMN1; SMN2 (0.74) | SMN1; SMN2MEN1KMT2AGAAMAPT | |
| SCHEMBL29712398 | 0.75 | SMN1; SMN2 (0.74) | SMN1; SMN2MEN1KMT2AGAAMAPT | |
| SCHEMBL28987838 | 0.73 | SMN1; SMN2 (0.80) | SMN1; SMN2MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |