Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753741 | 1.00 | DRD1 (0.39) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4753709 | 0.91 | DRD1 (0.40) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4753713 | 0.91 | DRD1 (0.40) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4753376 | 0.89 | DRD1 (0.41) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL13985519 | 0.88 | DRD1 (0.41) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4755057 | 0.88 | DRD1 (0.41) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4911234 | 0.80 | DRD1 (0.42) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4755753 | 0.79 | DRD1 (0.41) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4755752 | 0.79 | DRD1 (0.41) | DRD1DRD5POLBGRM1KMT2A | |
| SCHEMBL4753362 | 0.79 | SMN1; SMN2 (0.40) | DRD1DRD5POLBKMT2AGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |