Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705535 | 0.88 | MAPT (0.50) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL27475817 | 0.83 | KMT2A (0.51) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL3899416 | 0.82 | DHODH (0.55) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL8142880 | 0.78 | PLA2G2A (0.54) | ALDH1A1KDM4EHPGDHSD17B10PLA2G10 | |
| SCHEMBL38661529 | 0.78 | PLA2G2A (0.54) | ALDH1A1KDM4EHPGDHSD17B10PLA2G10 | |
| SCHEMBL7104600 | 0.78 | MEN1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL12088076 | 0.78 | MEN1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL7020881 | 0.78 | MAPT (0.51) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7045154 | 0.78 | MAPT (0.56) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL7797045 | 0.78 | MAPT (0.48) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459284-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-12-02 | — | — | US | disclosed |