Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 11/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985741 | 0.96 | AURKA (0.43) | AURKAPPARDTBK1 | |
| SCHEMBL4756460 | 0.90 | AURKA (0.43) | AURKAPPARD | |
| SCHEMBL4754628 | 0.89 | TBK1 (0.40) | AURKAPPARDTBK1 | |
| SCHEMBL210953 | 0.88 | AURKA (0.54) | AURKATBK1GNRHR | |
| SCHEMBL13985647 | 0.87 | AURKA (0.51) | AURKATBK1 | |
| SCHEMBL13985729 | 0.86 | TBK1 (0.44) | AURKATBK1GNRHR | |
| SCHEMBL212761 | 0.85 | AURKA (0.57) | AURKA | |
| SCHEMBL210870 | 0.84 | AURKA (0.42) | AURKATBK1 | |
| SCHEMBL209563 | 0.84 | AURKA (0.57) | AURKA | |
| SCHEMBL4754616 | 0.84 | PPARD (0.40) | AURKAPPARDTBK1PRMT5GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |