Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987169 | 0.98 | KDM4E (0.43) | KDM4ELMNAALDH1A1KMT2AKCNK3 | |
| SCHEMBL13988029 | 0.91 | KDM4E (0.45) | KDM4ELMNAALDH1A1KMT2AKCNK3 | |
| SCHEMBL9358766 | 0.88 | KDM4E (0.43) | KDM4ELMNAALDH1A1KMT2AKCNK3 | |
| SCHEMBL4853328 | 0.83 | HSD17B10 (0.39) | KDM4ELMNAALDH1A1KMT2ACYP3A4 | |
| SCHEMBL5359312 | 0.79 | KDM4E (0.41) | KDM4ELMNAALDH1A1KMT2AGAA | |
| SCHEMBL5364385 | 0.78 | KDM4E (0.40) | KDM4ELMNAALDH1A1KMT2AGAA | |
| SCHEMBL9864996 | 0.78 | BCHE (0.52) | ACHE | |
| SCHEMBL4748040 | 0.77 | KDM4E (0.41) | KDM4ELMNAALDH1A1KMT2AGAA | |
| SCHEMBL5917684 | 0.76 | KDM4E (0.43) | KDM4ELMNAALDH1A1KMT2AKCNK3 | |
| SCHEMBL6048316 | 0.76 | KDM4E (0.42) | KDM4ELMNAALDH1A1KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |