Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4852382 | 0.99 | ACHE (0.49) | ACHEHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL13987290 | 0.99 | ACHE (0.49) | ACHEHTR1ADRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4860519 | 0.98 | ACHE (0.48) | ACHEHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL13987331 | 0.94 | ACHE (0.51) | ACHE | |
| SCHEMBL13987344 | 0.94 | ACHE (0.50) | ACHE | |
| Hydrochloric Acid SCHEMBL4860715 | 0.93 | ACHE (0.49) | ACHE | |
| SCHEMBL13987311 | 0.90 | NPC1 (0.53) | ACHE | |
| SCHEMBL6634113 | 0.89 | ACHE (0.47) | ACHEHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL4850546 | 0.89 | ACHE (0.50) | ACHEHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL13987316 | 0.89 | NPC1 (0.53) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |