Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4860929 | 0.99 | ACHE (0.46) | ACHEMAPTEGFRERBB2ERBB4 | |
| Hydrochloric Acid SCHEMBL27593258 | 0.96 | ACHE (0.46) | ACHEMAPTEGFRERBB2ERBB4 | |
| SCHEMBL13987380 | 0.91 | ACHE (0.47) | ACHEMAPT | |
| Hydrochloric Acid SCHEMBL4891016 | 0.90 | MAPT (0.43) | ACHEMAPT | |
| Hydrochloric Acid SCHEMBL4861521 | 0.90 | ACHE (0.46) | ACHEMAPT | |
| SCHEMBL13987383 | 0.88 | MAPT (0.43) | ACHEMAPT | |
| SCHEMBL13987379 | 0.88 | MAPT (0.47) | ACHEMAPT | |
| Hydrochloric Acid SCHEMBL4861346 | 0.87 | MAPT (0.42) | ACHEMAPT | |
| SCHEMBL27593183 | 0.87 | ACHE (0.47) | ACHEMAPT | |
| SCHEMBL13987386 | 0.86 | MAPT (0.43) | ACHEMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |