Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4885227 | 0.99 | NAMPT (0.45) | NAMPTMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13987387 | 0.89 | MAPT (0.46) | NAMPTMAPTPOLBTHRBADRB2 | |
| SCHEMBL13987447 | 0.89 | THRB (0.51) | MAPTRAB9ASMN1; SMN2TP53POLB | |
| SCHEMBL13987353 | 0.89 | POLB (0.47) | MAPTSMN1; SMN2PKMPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL4879275 | 0.89 | MAPT (0.46) | NAMPTMAPTPOLBTHRBADRB2 | |
| Hydrochloric Acid SCHEMBL4851408 | 0.88 | THRB (0.50) | MAPTRAB9ASMN1; SMN2TP53POLB | |
| SCHEMBL13987391 | 0.88 | POLB (0.47) | MAPTSMN1; SMN2PKMPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL4888527 | 0.88 | POLB (0.47) | MAPTSMN1; SMN2PKMPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL4851829 | 0.87 | POLB (0.46) | MAPTSMN1; SMN2PKMPOLBALDH1A1 | |
| SCHEMBL4858163 | 0.86 | NPC1 (0.43) | NAMPTMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |