Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4862663 | 0.99 | SMN1; SMN2 (0.48) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| SCHEMBL13987487 | 0.87 | NPC1 (0.40) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL4860545 | 0.86 | NPC1 (0.39) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| SCHEMBL13987486 | 0.85 | TAAR1 (0.42) | ALDH1A1CA1CA2CA12CA9 | |
| Hydrochloric Acid SCHEMBL4857039 | 0.84 | TAAR1 (0.42) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL4851983 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| SCHEMBL5576935 | 0.83 | PTGDR2 (0.38) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL5576999 | 0.82 | PTGDR2 (0.37) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| SCHEMBL4862735 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL27611289 | 0.79 | CA2 (0.41) | SMN1; SMN2KLF5LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |