Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375825 | 0.81 | TSHR (0.50) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL22921004 | 0.80 | EPHX2 (0.42) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL1353297 | 0.79 | HDAC1 (0.42) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL13059994 | 0.76 | NPY5R (0.42) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL16062693 | 0.76 | POLB (0.46) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL2493713 | 0.76 | TSHR (0.44) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL23822678 | 0.74 | TSHR (0.43) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL915242 | 0.74 | TSHR (0.43) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL25923558 | 0.74 | TSHR (0.43) | HDAC1NPY5RCCNT1CDK9TSHR | |
| SCHEMBL916542 | 0.74 | ESR1 (0.48) | HDAC1NPY5RTSHRPOLBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459106-B2 | Materials, methods, and uses for photochemical generation of acids and/or radical species | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-12-02 | — | — | US | disclosed |