Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.42 |
| ▸ | CDK9 | P50750 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375825 | 0.94 | TSHR (0.50) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL17485921 | 0.93 | HDAC1 (0.40) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL3109529 | 0.93 | NPY5R (0.49) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL915420 | 0.91 | EGFR (0.44) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL12889588 | 0.91 | HDAC1 (0.40) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL13321993 | 0.88 | ALDH1A1 (0.41) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL12960341 | 0.88 | HRH3 (0.55) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL915615 | 0.88 | RARB (0.49) | TSHRTLR8TLR7MAPT | |
| SCHEMBL16062693 | 0.88 | POLB (0.46) | TSHRNPY5RHDAC1CCNT1CDK9 | |
| SCHEMBL917302 | 0.87 | RARB (0.51) | HDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400793-A1 | COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2024-12-05 | — | — | US | claimed |
| CN-114307893-B | Reaction device and process method suitable for continuous synthesis of fluorescent whitening agent | 沈阳化工研究院有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-114307893-A | Reaction device and process method suitable for continuous synthesis of fluorescent whitening agent | 沈阳化工研究院有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-7078465-B2 | Reacting paraformaldehyde with hydrogen bromide to form bis-bromomethyl ether as chemical intermediates; reacting biphenyl to form 4,4'-bis-(bromomethyl)-biphenyl, futher reacting with triethylphosphite to form 4,4'-bis-(diethylphosphonomethyl)-biphenyl; less hazardous, two stage processes | MAKHTESHIM CHEMICAL WORKS, LTD. (IL) | 2006-07-18 | — | — | US | claimed |
| US-20040242799-A1 | Reacting paraformaldehyde with hydrogen bromide to form bis-bromomethyl ether as chemical intermediates; reacting biphenyl to form 4,4'-bis-(bromomethyl)-biphenyl, futher reacting with triethylphosphite to form 4,4'-bis-(diethylphosphonomethyl)-biphenyl; less hazardous, two stage processes | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2004-12-02 | — | — | US | claimed |
| EP-1421050-A1 | PROCESS TO BROMOMETHYLATE AROMATIC COMPOUNDS | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2004-05-26 | — | — | EP | claimed |
| WO-2003018518-A1 | PROCESS TO BROMOMETHYLATE AROMATIC COMPOUNDS | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2003-03-06 | — | — | WO | claimed |
| US-20240400793-A1 | COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2024-12-05 | — | — | US | disclosed |
| CN-114307893-B | Reaction device and process method suitable for continuous synthesis of fluorescent whitening agent | 沈阳化工研究院有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114307893-A | Reaction device and process method suitable for continuous synthesis of fluorescent whitening agent | 沈阳化工研究院有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114307892-A | Multistage collision mixing micro-reactor and application | 沈阳化工研究院有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20210319957-A1 | NOVEL COMPOUND, AND COMPOSITION FOR FORMING HOLE TRANSPORTING LAYER FOR PEROVSKITE SOLAR CELLS | Tokyo Chemical Industry Co., Ltd. (JP) | 2021-10-14 | — | — | US | disclosed |
| US-20210284608-A1 | OPTICAL DATA COMMUNICATION SYSTEM COMPRISING PARA-PHENYLENEVINYLENES AND SPECIFIC PARA-PHENYLENEVINYLENES | BASF SE (DE) | 2021-09-16 | — | — | US | disclosed |
| WO-1999024394-A2 | COMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | UNIVERSITY OF PITTSBURGH (US) | 1999-05-20 | — | — | WO | disclosed |
| WO-1998047969-A1 | ALKYL, ALKENYL AND ALKYNYL CHRYSAMINE G DERIVATIVES FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION | UNIVERSITY OF PITTSBURGH (US) | 1998-10-29 | — | — | WO | disclosed |
| US-5382465-A | Durability | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0300770-B1 | Polarizing film containing an anthraquinonic colorant | MITSUI TOATSU CHEMICALS (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5252769-A | Anthraquinonic colorant and polarizing film containing the colorant | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0300770-A2 | Polarizing film containing an anthraquinonic colorant | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-01-25 | — | — | EP | disclosed |
| US-4118560-A | Substituted 1,4-bis-styrylbenzene and 4,4'-bis styrylbiphenyl and their use as optical brightners | CIBA-GEIGY CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284608-A1 | OPTICAL DATA COMMUNICATION SYSTEM COMPRISING PARA-PHENYLENEVINYLENES AND SPECIFIC PARA-PHENYLENEVINYLENES | OR10J3, OXER1, CDC73 | TSHR 3262/4885NPY5R 3409/4885HDAC1 4880/4885 |
| US-20040242799-A1 | Reacting paraformaldehyde with hydrogen bromide to form bis-bromomethyl ether as chemical intermediates; reacting biphenyl to form 4,4'-bis-(bromomethyl)-biphenyl, futher reacting with triethylphosphite to form 4,4'-bis-(diethylphosphonomethyl)-biphenyl; less hazardous, two stage processes | FGB, FHIT, PBRM1 | TSHR 1145/4885NPY5R 3958/4885HDAC1 783/4885 |
| US-20210319957-A1 | NOVEL COMPOUND, AND COMPOSITION FOR FORMING HOLE TRANSPORTING LAYER FOR PEROVSKITE SOLAR CELLS | SLC43A1, SLC26A3, KCNT1 | TSHR 3012/4885NPY5R 2749/4885HDAC1 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.