Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.58 |
| ▸ | ANPEP | P15144 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022177 | 0.86 | DPP4 (0.64) | DPP4NR1H3NR1H2ANPEP | |
| SCHEMBL29366407 | 0.84 | DPP4 (0.78) | DPP4NR1H3NR1H2ANPEPCASP3 | |
| SCHEMBL2820118 | 0.84 | DPP4 (0.78) | DPP4NR1H3NR1H2ANPEPCASP3 | |
| SCHEMBL14458034 | 0.84 | ANPEP (0.49) | DPP4NR1H3NR1H2ANPEPKMT2A | |
| SCHEMBL10269051 | 0.83 | ANPEP (0.43) | DPP4NR1H3NR1H2ANPEPKDM4E | |
| SCHEMBL12206252 | 0.83 | ANPEP (0.45) | DPP4NR1H3NR1H2ANPEPKDM4E | |
| SCHEMBL13784709 | 0.81 | ANPEP (0.43) | DPP4NR1H3NR1H2ANPEP | |
| SCHEMBL179197 | 0.80 | DPP4 (0.45) | DPP4NR1H3NR1H2ANPEP | |
| SCHEMBL12066788 | 0.80 | DPP4 (0.45) | DPP4NR1H3NR1H2ANPEP | |
| SCHEMBL12066773 | 0.79 | ANPEP (0.44) | DPP4NR1H3NR1H2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306134-A1 | THALIDOMIDE ANALOGS FOR TREATING VASCULAR ABNORMALITIES | CHARLESSON, LLC | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306134-A1 | THALIDOMIDE ANALOGS FOR TREATING VASCULAR ABNORMALITIES | VEGFA, FLT1, VCAM1 | DPP4 4355/4885NR1H3 4388/4885NR1H2 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.