SCHEMBL13992138

SCHEMBL13992138

O=C(Nc1cccnn1)N1CCN(Cc2ccc(O)c(O)c2)CC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3636693 0.87 FAAH (0.67) FAAH
SCHEMBL3637258 0.87 FAAH (0.75) FAAH
SCHEMBL3641485 0.87 FAAH (0.67) FAAH
SCHEMBL3730909 0.82 FAAH (0.68) FAAH
SCHEMBL3638592 0.81 FAAH (0.70) FAAH
SCHEMBL3636102 0.80 FAAH (1.00) FAAH
SCHEMBL3644202 0.79 FAAH (0.80) FAAH
SCHEMBL13913027 0.79 FAAH (0.65) FAAH
SCHEMBL13333169 0.76 FAAH (0.68) FAAH
SCHEMBL3640772 0.76 FAAH (0.61) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008153752-A2 HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2008-12-18 WO disclosed