Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13992151 | 0.89 | ALOX5 (0.46) | NPSR1SLC6A3ALOX5RAB9APTGER4 | |
| SCHEMBL17468787 | 0.72 | ALOX5 (0.51) | ALOX5RAB9AMAPTKDM4EPOLB | |
| SCHEMBL3406206 | 0.72 | NPSR1 (0.46) | NPSR1SLC6A3PTGER4MAPTKDM4E | |
| SCHEMBL13992157 | 0.71 | ALOX5 (0.46) | NPSR1ALOX5RAB9APTGER4MAPT | |
| SCHEMBL9566160 | 0.71 | ALOX5 (0.50) | ALOX5RAB9AMAPTKDM4EPOLB | |
| SCHEMBL657541 | 0.70 | — | — | |
| SCHEMBL3100001 | 0.70 | — | — | |
| SCHEMBL3906087 | 0.70 | FFAR1 (0.58) | NPSR1PTGER4KDM4EALDH1A1DDAH1 | |
| SCHEMBL10937131 | 0.69 | NPSR1 (0.91) | NPSR1SLC6A3PTGER4POLBL3MBTL1 | |
| SCHEMBL8342204 | 0.69 | NPSR1 (0.52) | NPSR1SLC6A3ALOX5MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150192555-A1 | Methods and Devices for Analytical Sensing of Biogenic Amines | UNIVERSITY OF SOUTH CAROLINA | 2015-07-09 | — | — | US | disclosed |
| US-8927293-B2 | Methods and devices for analytical sensing of biogenic amines | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-01-06 | — | — | US | disclosed |
| US-20080299669-A1 | Methods and devices for analytical sensing of biogenic amines | SOUTH CAROLINA, UNIVERSITY OF | 2008-12-04 | — | — | US | disclosed |