Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945700 | 0.92 | HPGD (0.49) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4945331 | 0.91 | ALDH1A1 (0.54) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4944749 | 0.91 | HPGD (0.49) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4942023 | 0.91 | HPGD (0.48) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4943640 | 0.89 | ALDH1A1 (0.51) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4944169 | 0.89 | HPGD (0.47) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4946428 | 0.88 | NPSR1 (0.52) | HPGDALDH1A1NPSR1MAPTMAPK1 | |
| SCHEMBL4945459 | 0.88 | TP53 (0.53) | HPGDALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL4940554 | 0.87 | ALDH1A1 (0.47) | HPGDALDH1A1NPSR1MAPTTP53 | |
| SCHEMBL4937715 | 0.86 | ALDH1A1 (0.53) | HPGDALDH1A1NPSR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468385-B2 | Triazoles as oxytocin antagonists | LABORATOIRES SERONO SA (CH) | 2008-12-23 | — | — | US | disclosed |