⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200043 | 1.00 | — | — | |
| SCHEMBL13619489 | 0.78 | — | — | |
| SCHEMBL13992412 | 0.75 | SLC6A2 (0.42) | — | |
| SCHEMBL13596208 | 0.70 | ALOX5 (0.44) | — | |
| SCHEMBL13596237 | 0.70 | ALOX5 (0.44) | — | |
| SCHEMBL24297510 | 0.66 | POLB (0.32) | — | |
| SCHEMBL68248 | 0.65 | CACNA2D1 (0.32) | — | |
| SCHEMBL68246 | 0.65 | CACNA2D1 (0.32) | — | |
| SCHEMBL9305313 | 0.65 | CACNA2D1 (0.32) | — | |
| SCHEMBL13166778 | 0.65 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462592-B2 | Compositions and methods for polynucleotide delivery | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2008-12-09 | — | — | US | disclosed |