Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720003 | 1.00 | KDM4E (0.54) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL19873269 | 1.00 | KDM4E (0.54) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL11671585 | 0.96 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Phosphoric Acid SCHEMBL18193011 | 0.90 | KDM4E (0.45) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL11672048 | 0.86 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL22321695 | 0.86 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL10337937 | 0.86 | KDM4E (0.54) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL8839893 | 0.85 | LMNA (0.36) | KDM4ELMNAL3MBTL1TDP1USP2 | |
| SCHEMBL724112 | 0.85 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL9444652 | 0.85 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758468-B1 | TASTE IMPROVING SUBSTANCES | GIVAUDAN NEDERLAND SERVICES BV (NL) | 2011-03-02 | — | — | EP | claimed |