Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399347 | 0.92 | HTR2A (0.56) | HTR2AMAPTSMN1; SMN2NPSR1AR | |
| SCHEMBL1399206 | 0.86 | HTR2A (0.58) | HTR2AMAPTSMN1; SMN2NPSR1AR | |
| SCHEMBL1399261 | 0.85 | HTR2A (0.60) | HTR2AMAPTSMN1; SMN2NPSR1IDO1 | |
| SCHEMBL1399279 | 0.85 | AR (0.47) | HTR2AMAPTSMN1; SMN2NPSR1AR | |
| SCHEMBL1399191 | 0.81 | HTR2A (0.55) | HTR2AIDO1TRPM8MPOTUBB4A | |
| SCHEMBL1399335 | 0.80 | HTR2A (0.59) | HTR2AMAPTSMN1; SMN2NPSR1AR | |
| SCHEMBL1399393 | 0.79 | HTR2A (0.43) | HTR2AMAPTSMN1; SMN2NPSR1AR | |
| SCHEMBL1399386 | 0.79 | MPO (0.56) | HTR2AMAPTSMN1; SMN2NPSR1IDO1 | |
| SCHEMBL1399308 | 0.79 | HTR2A (0.58) | HTR2AMAPTIDO1TRPM8TUBB4A | |
| SCHEMBL1399208 | 0.78 | AR (0.47) | HTR2AMAPTSMN1; SMN2NPSR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |