Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399320 | 0.88 | MEN1 (0.46) | HTR2AMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL1399237 | 0.85 | IFNAR1 (0.43) | SMN1; SMN2GAAMEN1RAB9AKMT2A | |
| SCHEMBL1399403 | 0.81 | HTR2A (0.55) | HTR2AMAPTSMN1; SMN2NPSR1HTR1D | |
| SCHEMBL1399393 | 0.81 | HTR2A (0.43) | HTR2AMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL2154532 | 0.77 | TAAR1 (0.62) | HTR2AMAPTGAAMEN1RAB9A | |
| SCHEMBL1399206 | 0.76 | HTR2A (0.58) | HTR2AMAPTSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL1399281 | 0.76 | HTR2A (0.58) | HTR2AMAPTSMN1; SMN2NPSR1SLC6A4 | |
| SCHEMBL1399490 | 0.74 | IDO1 (0.59) | HTR2AHTR1DSLC6A4HTR1AHTR1B | |
| SCHEMBL4633098 | 0.74 | HTR2A (0.58) | HTR2AMEN1KMT2AHTR1DSLC6A4 | |
| SCHEMBL4633963 | 0.74 | HTR2A (0.54) | HTR2AMEN1KMT2AHTR1DSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |