Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399293 | 0.86 | IFNAR1 (0.54) | IFNAR1LMNARECQLSMN1; SMN2SLC6A2 | |
| SCHEMBL1399466 | 0.84 | IFNAR1 (0.51) | IFNAR1LMNARECQLSMN1; SMN2SLC6A2 | |
| SCHEMBL1399315 | 0.84 | IFNAR1 (0.51) | IFNAR1LMNARECQLSMN1; SMN2SLC6A2 | |
| SCHEMBL1399212 | 0.84 | IFNAR1 (0.51) | IFNAR1LMNARECQLSMN1; SMN2SLC6A2 | |
| SCHEMBL1399262 | 0.84 | IDO1 (0.39) | IFNAR1SLC6A4CYP2A6GPR84 | |
| SCHEMBL1399273 | 0.82 | KMT2A (0.49) | IFNAR1MEN1POLBKMT2A | |
| SCHEMBL1399370 | 0.82 | HTR2A (0.47) | LMNASLC6A2CYP2A6 | |
| SCHEMBL1399362 | 0.81 | IFNAR1 (0.60) | IFNAR1LMNARECQLSMN1; SMN2SLC6A2 | |
| SCHEMBL31415122 | 0.78 | GPR84 (0.50) | SLC6A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1399373 | 0.78 | GPR84 (0.49) | IFNAR1LMNARECQLSMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |