Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399195 | 0.90 | IDO1 (0.51) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4391401 | 0.88 | HTR2A (0.56) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399402 | 0.86 | GFER (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399260 | 0.85 | IDO1 (0.53) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4632786 | 0.85 | IDO1 (0.51) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399483 | 0.85 | IDO1 (0.64) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3182311 | 0.84 | GPR84 (0.45) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399282 | 0.84 | IDO1 (0.49) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399362 | 0.84 | IFNAR1 (0.60) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1399485 | 0.83 | IDO1 (0.56) | IDO1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |