Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.80 |
| ▸ | THRB | P10828 | 8/20 | 0.80 |
| ▸ | BLM | P54132 | 7/20 | 0.80 |
| ▸ | RECQL | P46063 | 6/20 | 0.80 |
| ▸ | TOP2A | P11388 | 5/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.80 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.80 |
| ▸ | HTT | P42858 | 4/20 | 0.80 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.80 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.80 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.80 |
| ▸ | FYN | P06241 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26961130 | 0.95 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL16622415 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| Hydrochloric Acid SCHEMBL28246402 | 0.95 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL28260380 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL23117782 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL25228806 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL30465123 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL20307182 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL10014019 | 0.95 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL20982173 | 0.94 | MEN1 (0.79) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583544-B2 | Remote loading of sparingly water-soluble drugs into lipid vesicles | CELATOR PHARMACEUTICALS, INC. (US) | 2023-02-21 | — | — | US | claimed |
| WO-2022124898-A1 | AURISTATIN-LOADED LIPOSOMES AND USES THEREOF. | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2022-06-16 | — | — | WO | claimed |
| US-20210008091-A1 | REMOTE LOADING OF SPARINGLY WATER-SOLUBLE DRUGS INTO LIPID VESICLES | Jazz Pharmaceuticals Therapeutics, Inc. | 2021-01-14 | — | — | US | claimed |
| US-20190105339-A1 | REMOTE LOADING OF SPARINGLY WATER-SOLUBLE DRUGS INTO LIPID VESICLES | ZONEONE PHARMA INC (US) | 2019-04-11 | — | — | US | claimed |
| US-20180344644-A1 | IMPROVED STABILITY OF LIPOSOME FORMULATIONS AND USES THEREOF | IKARIA THERAPEUTICS LLC | 2018-12-06 | — | — | US | claimed |
| EP-3352733-A1 | IMPROVED STABILITY OF LIPOSOME FORMULATIONS AND USES THEREOF | Mallinckrodt LLC (US) | 2018-08-01 | — | — | EP | claimed |
| US-20170340624-A1 | Liposomes Useful for Drug Delivery | HERMES BIOSCIENCES, INC. | 2017-11-30 | — | — | US | claimed |
| US-20170231911-A1 | METHODS AND COMPOSITIONS FOR IMPROVING OUTCOMES OF LIPOSOMAL CHEMOTHERAPY | MERRIMACK PHARMACEUTICALS, INC. | 2017-08-17 | — | — | US | claimed |
| US-20170224715-A1 | REMOTE LOADING OF SPARINGLY WATER-SOLUBLE DRUGS INTO LIPID VESICLES | Jazz Pharmaceuticals Therapeutics, Inc. | 2017-08-10 | — | — | US | claimed |
| EP-3177269-A1 | REMOTE LOADING OF SPARINGLY WATER-SOLUBLE DRUGS INTO LIPID VESICLES | Zoneone Pharma, Inc. (US) | 2017-06-14 | — | — | EP | claimed |
| US-20090081121-A1 | LIPOSOME COMPOSITIONS USEFUL FOR TUMOR IMAGING AND TREATMENT | NATIONAL HEALTH RESEARCH INSTITUTE (TW) | 2009-03-26 | — | — | US | claimed |
| US-20070116753-A1 | Liposomes useful for drug delivery | HERMES BIOSCIENCES, INC. (US) | 2007-05-24 | — | — | US | claimed |
| EP-1746976-A1 | LIPOSOMES USEFUL FOR DRUG DELIVERY | Hermes Biosciences, Inc. (US) | 2007-01-31 | — | — | EP | claimed |
| WO-2005107712-A1 | LIPOSOMES USEFUL FOR DRUG DELIVERY | HERMES BIOSCIENCES, INC. (US) | 2005-11-17 | — | — | WO | claimed |
| EP-1423126-A2 | TREATMENT OF HYPERPROLIFERATIVE CONDITIONS OF BODY SURFACES | Valderm APS (DK) | 2004-06-02 | — | — | EP | claimed |
| WO-2003015759-A2 | TREATMENT OF HYPERPROLIFERATIVE CONDITIONS OF BODY SURFACES | VALDERM APS (DK) | 2003-02-27 | — | — | WO | claimed |
| EP-0361894-B1 | Loading and controlled release of amphiphatic molecules to and from liposomes | YISSUM RES DEV CO (IL) | 1994-11-09 | — | — | EP | claimed |
| EP-0274174-B1 | LIPOSOME/ANTHRAQUINONE DRUG COMPOSITION AND METHOD | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1992-11-04 | — | — | EP | claimed |
| US-5043166-A | Antitumor agents; side effect reduction | HADASIT MEDICAL RESEARCH, INC. (IL) | 1991-08-27 | — | — | US | claimed |
| EP-0361894-A2 | Loading and controlled release of amphiphatic molecules to and from liposomes | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1990-04-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180344644-A1 | IMPROVED STABILITY OF LIPOSOME FORMULATIONS AND USES THEREOF | SGMS2, SGMS1, LIPA | MEN1 586/4885KMT2A 3844/4885THRB 4010/4885 |
| US-20070116753-A1 | Liposomes useful for drug delivery | ABHD16A, LIPA, AGPAT5 | MEN1 785/4885KMT2A 1607/4885THRB 4827/4885 |
| US-20170340624-A1 | Liposomes Useful for Drug Delivery | ABHD16A, LIPA, AGPAT5 | MEN1 785/4885KMT2A 1607/4885THRB 4827/4885 |
| US-20170231911-A1 | METHODS AND COMPOSITIONS FOR IMPROVING OUTCOMES OF LIPOSOMAL CHEMOTHERAPY | LIPA, SGMS1, SGMS2 | MEN1 1339/4885KMT2A 2495/4885THRB 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.