Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286764 | 0.85 | FAP (0.71) | DPP4PREPFAPDPP7 | |
| SCHEMBL3808079 | 0.84 | PREP (0.72) | DPP4PREPDPP7 | |
| SCHEMBL3808076 | 0.84 | PREP (0.72) | DPP4PREPDPP7 | |
| SCHEMBL30182960 | 0.75 | NPC1 (0.61) | DPP4PREPFAPMEN1KMT2A | |
| SCHEMBL2230140 | 0.74 | NPC1 (0.79) | CARM1PRMT6NPSR1MEN1KMT2A | |
| SCHEMBL124395 | 0.74 | NPC1 (0.79) | CARM1PRMT6NPSR1MEN1KMT2A | |
| SCHEMBL16104917 | 0.74 | DPP4 (0.69) | DPP4NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3808184 | 0.73 | DPP4 (0.67) | DPP4PREPDPP7 | |
| SCHEMBL3808180 | 0.73 | DPP4 (0.67) | DPP4PREPDPP7 | |
| SCHEMBL12425958 | 0.73 | NPC1 (0.67) | CARM1PRMT6NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997533-A1 | Heterocyclic boronic acid compounds, dipeptidyl peptidase IV inhibitors | Phenomix Corporation (US) | 2008-12-03 | — | — | EP | disclosed |