Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445161 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL13997361 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL13997317 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL13997340 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL13997326 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL17445167 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL13997312 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BCA1CA2TDP1 | |
| SCHEMBL16217782 | 0.94 | TDP1 (0.50) | CA1CA2TDP1ATMCTSS | |
| SCHEMBL19975659 | 0.94 | TDP1 (0.50) | CA1CA2TDP1ATMCTSS | |
| SCHEMBL17445170 | 0.93 | ITGB3 (0.51) | ITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238697-B2 | Polymeric materials and methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-19 | — | — | US | disclosed |
| US-20080317861-A1 | Polymeric Materials and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080317861-A1 | Polymeric Materials and Methods | CD44, IAPP, CA14 | ITGB3 623/4885ITGA2B 1357/4885CA1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.