Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997299 | 1.00 | CA2 (0.38) | CA2MAPK1NPSR1MAPTGAA | |
| SCHEMBL13997315 | 1.00 | CA2 (0.38) | CA2MAPK1NPSR1MAPTGAA | |
| SCHEMBL8895562 | 0.87 | MAPK1 (0.41) | CA2MAPK1NPSR1GAAPGD | |
| SCHEMBL5795974 | 0.79 | MAPK1 (0.36) | MAPK1NPSR1GAAPGD | |
| SCHEMBL4411311 | 0.79 | MAPK1 (0.36) | MAPK1NPSR1GAAPGD | |
| SCHEMBL15514446 | 0.78 | SUCNR1 (0.39) | CA2MAPK1NPSR1MAPTGAA | |
| SCHEMBL13997318 | 0.78 | SUCNR1 (0.39) | CA2MAPK1NPSR1MAPTGAA | |
| SCHEMBL5048000 | 0.78 | SUCNR1 (0.39) | CA2MAPK1NPSR1MAPTGAA | |
| SCHEMBL14007051 | 0.78 | SUCNR1 (0.39) | CA2MAPK1NPSR1MAPTGAA | |
| SCHEMBL29373888 | 0.76 | GAA (0.50) | CA2MAPK1NPSR1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289500-B2 | Saccharide-peptide hydrogels | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-22 | — | — | US | disclosed |
| US-9238697-B2 | Polymeric materials and methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-19 | — | — | US | disclosed |
| US-9238697-B2 | Polymeric materials and methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-19 | — | — | US | disclosed |
| US-20140242123-A1 | SACCHARIDE-PEPTIDE HYDROGELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-08-28 | — | — | US | disclosed |
| US-20080317861-A1 | Polymeric Materials and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080317861-A1 | Polymeric Materials and Methods | CD44, IAPP, CA14 | CA2 814/4885MAPK1 3355/4885NPSR1 1373/4885 |
| US-20140242123-A1 | SACCHARIDE-PEPTIDE HYDROGELS | IAPP, CD44, HPSE | CA2 2579/4885MAPK1 2157/4885NPSR1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.