Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166808 | 0.85 | KDM4E (0.56) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL31146399 | 0.85 | KDM4E (0.56) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL29415434 | 0.84 | KDM4E (1.00) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL2805779 | 0.84 | KDM4E (1.00) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL1621957 | 0.81 | KDM4E (0.69) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL3985154 | 0.81 | KDM4E (0.74) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL1620204 | 0.79 | KDM4E (0.72) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL30388663 | 0.79 | KDM4E (0.72) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL1037203 | 0.79 | KDM4E (0.72) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL15067394 | 0.79 | KDM4E (0.72) | KDM4ETDP1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041306-A | 4- hydroxyl -2- quinolone-nitrogen-(4- quinazolinone) -3- carboxamides derivatives | 中国医学科学院药物研究所 | 2019-07-23 | — | — | CN | disclosed |
| CN-102015705-B | Fused heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2013-11-13 | — | — | CN | disclosed |
| CN-102015705-A | Fused heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-04-13 | — | — | CN | disclosed |
| US-20080311150-A1 | Novel sequences encoding hepatitis C virus glycoproteins | DUMONCEAUX JULIE | 2008-12-18 | — | — | US | disclosed |
| US-7361503-B2 | Sequences encoding hepatitis C virus glycoproteins | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2008-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311150-A1 | Novel sequences encoding hepatitis C virus glycoproteins | HAVCR2, EEA1, SELPLG | KDM4E 3908/4885TDP1 3943/4885LMNA 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.