Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146399 | 1.00 | KDM4E (0.56) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL13997679 | 0.85 | KDM4E (0.72) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1228041 | 0.81 | KDM4E (0.62) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1621884 | 0.81 | KDM4E (0.68) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8930304 | 0.80 | DAO (0.60) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1621957 | 0.80 | KDM4E (0.69) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2730936 | 0.77 | MAP2 (0.60) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30601629 | 0.77 | MAP2 (0.60) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5280341 | 0.77 | KDM4E (0.56) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL5528637 | 0.76 | KDM4E (0.59) | KDM4ETDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224172-B1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2007-04-04 | — | — | EP | claimed |
| CN-1589264-A | Method for the treatment of malignant tumours | ACTIVE BIOTECH AB (SE) | 2005-03-02 | — | — | CN | claimed |
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | claimed |
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | claimed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | claimed |
| CN-100390148-C | Method for the treatment of malignant tumours | ACTIVE BIOTECH AB (SE) | 2008-05-28 | — | — | CN | disclosed |
| EP-1224172-B1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| CN-1589264-A | Method for the treatment of malignant tumours | ACTIVE BIOTECH AB (SE) | 2005-03-02 | — | — | CN | disclosed |
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | disclosed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | disclosed |