SCHEMBL13998010

SCHEMBL13998010

O=C(O)c1cc(N2C(=O)C3C4C=CC(C4)C3C2=O)cc(N2C(=O)C3C4C=CC(C4)C3C2=O)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
USP2 O75604 1/20 0.51
TSHR P16473 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C19 P33261 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
NSD2 O96028 1/20 0.50
G6PD P11413 1/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194211 0.97 MEN1 (0.53) MEN1KMT2ASMN1; SMN2USP2TSHR
SCHEMBL13038585 0.87 USP2 (0.51) MEN1KMT2ASMN1; SMN2USP2TSHR
SCHEMBL3190391 0.85 MEN1 (0.68) MEN1KMT2ASMN1; SMN2CYP2C19L3MBTL1
SCHEMBL15101846 0.84 KMT2A (0.63) MEN1KMT2AUSP2TSHRCYP3A4
SCHEMBL3201443 0.84 KMT2A (0.63) MEN1KMT2AUSP2TSHRCYP3A4
SCHEMBL13998009 0.80 USP2 (0.57) SMN1; SMN2USP2TSHRCYP3A4CYP2C19
SCHEMBL5520649 0.79 SMN1; SMN2 (0.56) MEN1KMT2ASMN1; SMN2TSHRCYP3A4
SCHEMBL13983889 0.79 MEN1 (0.44) MEN1KMT2ASMN1; SMN2USP2TSHR
SCHEMBL17547338 0.78 TSHR (0.64) USP2TSHRCYP3A4CYP2C19NPSR1
SCHEMBL3181082 0.76 USP2 (0.57) SMN1; SMN2USP2TSHRCYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180009949-A1 DINADIC PHENYL AMINE REACTIVE ENDCAPS THE BOEING COMPANY 2018-01-11 US disclosed
US-9670325-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2017-06-06 US disclosed
US-9670325-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2017-06-06 US disclosed
US-9505864-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2016-11-29 US disclosed
US-9505864-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2016-11-29 US disclosed
US-20160208053-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-07-21 US disclosed
US-20160208053-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-07-21 US disclosed
US-9315633-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2016-04-19 US disclosed
US-9315633-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2016-04-19 US disclosed
US-20160060377-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-03-03 US disclosed
US-20160060377-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-03-03 US disclosed
US-20160060400-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-03-03 US disclosed
US-20160060400-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-03-03 US disclosed
EP-2990431-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS The Boeing Company (US) 2016-03-02 EP disclosed
US-20080300374-A1 DINADIC PHENYL AMINE REACTIVE ENDCAPS THE BOEING COMPANY 2008-12-04 US disclosed
US-20080300374-A1 DINADIC PHENYL AMINE REACTIVE ENDCAPS THE BOEING COMPANY 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180009949-A1 DINADIC PHENYL AMINE REACTIVE ENDCAPS PARN, AADAC, PARG MEN1 2295/4885KMT2A 1035/4885SMN1; SMN2 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.