Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494483 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2TSHRKMT2AMEN1HPGD | |
| SCHEMBL13318217 | 0.86 | ALDH1A1 (0.66) | SMN1; SMN2TSHRKMT2AMEN1HPGD | |
| SCHEMBL3194211 | 0.82 | MEN1 (0.53) | SMN1; SMN2TSHRKMT2AMEN1CYP2C19 | |
| SCHEMBL13038585 | 0.79 | USP2 (0.51) | SMN1; SMN2TSHRKMT2AMEN1CYP2C19 | |
| SCHEMBL13998010 | 0.79 | MEN1 (0.53) | SMN1; SMN2TSHRKMT2AMEN1CYP2C19 | |
| SCHEMBL5509559 | 0.77 | POLB (0.61) | SMN1; SMN2TSHRKMT2AMEN1HPGD | |
| SCHEMBL5515033 | 0.77 | KMT2A (0.64) | SMN1; SMN2TSHRKMT2AMEN1CYP2C19 | |
| SCHEMBL12599338 | 0.75 | KMT2A (0.61) | TSHRKMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL7178769 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2TSHRKMT2AMEN1HPGD | |
| SCHEMBL3190188 | 0.74 | KMT2A (0.57) | TSHRKMT2AMEN1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20060189771-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060041092-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-02-23 | — | — | US | disclosed |