Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520299 | 0.85 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL5040778 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL2600059 | 0.80 | ALDH1A1 (0.61) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL2068578 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL31119455 | 0.73 | — | — | |
| SCHEMBL91385 | 0.73 | — | — | |
| SCHEMBL20428004 | 0.72 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL29416967 | 0.72 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL13738228 | 0.72 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL18811661 | 0.71 | SLC6A2 (0.43) | ALDH1A1CHRNA4SLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686857-B1 | COMBINATION OF ACTIVE SUBSTANCES WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2008-12-10 | — | — | EP | disclosed |