Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 7/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000392 | 0.90 | RAB9A (0.39) | RAB9AEGFRERBB2ABCB1KDM4E | |
| SCHEMBL15630662 | 0.88 | RAB9A (0.37) | RAB9AEGFRERBB2ABCB1KDM4E | |
| SCHEMBL19049027 | 0.85 | RAB9A (0.36) | RAB9AEGFRERBB2ABCB1KDM4E | |
| SCHEMBL15291777 | 0.85 | KDM4E (0.39) | RAB9AABCB1KDM4EIKBKBALDH1A1 | |
| SCHEMBL22510702 | 0.84 | KDM4E (0.35) | RAB9AABCB1KDM4EALDH1A1 | |
| SCHEMBL14000383 | 0.84 | KDM4E (0.33) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13999921 | 0.84 | KDM4E (0.33) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15450395 | 0.84 | KDM4E (0.37) | RAB9AABCB1KDM4EIKBKBALDH1A1 | |
| SCHEMBL20980522 | 0.83 | PDE9A (0.34) | PDE9A | |
| SCHEMBL18607418 | 0.82 | RAB9A (0.36) | RAB9AABCB1KDM4EGPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000464-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |