Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001037 | 0.82 | CA1 (0.39) | CA1CA2CA12CA9 | |
| SCHEMBL500078 | 0.81 | CA1 (0.53) | CA1CA2CA12CA9 | |
| SCHEMBL500424 | 0.81 | CA1 (0.43) | CA1CA2CA12CA9 | |
| SCHEMBL500341 | 0.81 | CA1 (0.43) | CA1CA2CA12CA9 | |
| SCHEMBL10053280 | 0.81 | CA1 (0.43) | CA1CA2CA12CA9 | |
| SCHEMBL596084 | 0.78 | PDE4B (0.44) | CA1CA2 | |
| SCHEMBL12589670 | 0.77 | CA1 (0.40) | CA1CA2 | |
| SCHEMBL13996402 | 0.77 | CA1 (0.44) | CA1CA2CA12CA9 | |
| SCHEMBL500335 | 0.71 | CA1 (0.47) | CA1CA2CA12CA9 | |
| SCHEMBL596495 | 0.71 | CA1 (0.47) | CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465836-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |