Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388489 | 0.88 | GPR119 (0.62) | GPR119CYP2C9 | |
| SCHEMBL3161178 | 0.84 | GPR119 (0.49) | GPR119CYP2C9 | |
| SCHEMBL1893829 | 0.74 | GPR119 (0.66) | GPR119CYP2C9 | |
| SCHEMBL386065 | 0.74 | GPR119 (0.61) | GPR119CYP2C9 | |
| SCHEMBL387819 | 0.73 | GPR119 (0.65) | GPR119CYP2C9 | |
| SCHEMBL386216 | 0.73 | GPR119 (0.65) | GPR119CYP2C9 | |
| SCHEMBL389922 | 0.73 | GPR119 (0.62) | GPR119CYP2C9 | |
| SCHEMBL388773 | 0.73 | GPR119 (0.62) | GPR119CYP2C9 | |
| SCHEMBL1894615 | 0.73 | GPR119 (0.62) | GPR119CYP2C9 | |
| SCHEMBL389010 | 0.72 | GPR119 (0.79) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470699-B2 | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470699-B2 | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2008-12-30 | — | — | US | disclosed |