Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 13/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13489673 | 0.93 | CMA1 (0.68) | CMA1 | |
| SCHEMBL13490142 | 0.90 | CMA1 (0.56) | CMA1 | |
| SCHEMBL13172303 | 0.87 | CMA1 (0.65) | CMA1 | |
| SCHEMBL8290204 | 0.83 | CMA1 (0.66) | CMA1 | |
| SCHEMBL10330708 | 0.82 | CMA1 (0.83) | CMA1 | |
| SCHEMBL409980 | 0.81 | CMA1 (0.75) | CMA1 | |
| SCHEMBL409979 | 0.81 | CMA1 (0.75) | CMA1 | |
| SCHEMBL3141528 | 0.79 | CMA1 (0.78) | CMA1 | |
| SCHEMBL3141532 | 0.79 | CMA1 (0.78) | CMA1 | |
| SCHEMBL3238437 | 0.79 | CMA1 (0.72) | CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459444-B2 | Inhibitors of chymase | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-02 | — | — | US | disclosed |